Phofo ea Sinomenine Hydrochloride
Sinomenine Hydrochloride ke motsoako oa lik'hemik'hale o tsoang ho semela sa Sinomenium acutum, se fumanehang hangata Asia Bochabela. Ke alkaloid e 'nileng ea sebelisoa ka tloaelo meriana ea Sechaena bakeng sa thepa ea eona e khahlanong le ho ruruha le ea analgesic. Foromo ea hydrochloride ke letsoai le ntlafatsang ho qhibiliha ha motsoako le botsitso, ho etsa hore e be e loketseng haholoanyane bakeng sa tšebeliso ea meriana.
Sinomenine Hydrochloride e 'nile ea ithutoa bakeng sa liphello tsa eona tsa phekolo tse ka' nang tsa e-ba teng ho phekola maemo a kang ramatiki ea lefuba, ka lebaka la bokhoni ba eona ba ho fetola sesole sa 'mele le ho fokotsa ho ruruha. E sebetsa ka ho thibela tlhahiso ea li-cytokine tsa pro-inflammatory le bakena-lipakeng ba bang ba amehang karabelong ea ho ruruha.
Ntle le litlamorao tsa eona tse khahlanong le ho ruruha le li-analgesic, Sinomenine Hydrochloride e boetse e bonts'itse bokhoni ba ts'ireletso ea methapo, anti-fibrosis le anti-tumor lithutong tse fapaneng tsa pele ho nako.
Lebitso la Molao:(9a,13a,14a) -7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-morphinan-6-one, monohydrochloride
Nomoro ea CAS: 6080-33-7
Synonyms: Cucoline NSC 76021
Foromo ea molek'hule: C19H23NO4 • HCl
Boima ba 'mele: 365.9
Bohloeki: ≥98% E tiileng ka kristale
Solubility(Ithute ka Phapano ea Solubility)
DMF: 30 mg/ml
DMSO: 30 mg/ml
Ethanol: 5 mg/ml
PBS (pH 7.2): 5 mg/ml
Tšimoloho: Semela/Sinomenium acutum
Lintlha tsa ho Romela le ho Boloka:
Sebaka sa polokelo -20°C
Thomello: Mocheso oa Kamore
Botsitso: ≥ 4 lilemo
| Ntho | Tlhaloso | Sephetho |
| Assay(HPLC) | 98.0% | 98.12% |
| Ponahalo | Phofo e tšoeu | E lumellana |
| Boholo ba Karolo | 98% ho ea ho 80mesh | E lumellana |
| Monko o monate | Sebopeho | E lumellana |
| Latsoang | Sebopeho | E lumellana |
| Litšobotsi Tsa 'Mele | ||
| Tahlehelo ka ho Omisa | ≤0.5% | 0.38% |
| Molora | ≤0.5% | 0.46% |
| Litšepe tse boima | ||
| Litšepe tse boima (joalo ka Pb) | Litekanyetso tsa USP(<10ppm) | <10ppm |
| Arsenic(As) | ≤2ppm | 0.78ppm |
| Ketapele (Pb) | ≤2ppm | 1.13ppm |
| Cadmium(Cd) | ≤lppm | 0.36ppm |
| Mercary(Hg) | ≤0.1ppm | 0.01ppm |
| Masala a chefo e bolaeang likokoanyana | E sa fumanweng | E sa fumanweng |
| Kakaretso ea PlateCount | NMT 10000cfu/g | 680 cfu/g |
| Kakaretso ea Yeast & Mold | NMT 100cfu/g | 87 cfu/g |
| E.Coli | NMT 30cfu/g | 10 cfu/g |
| Salmonella | E mpe | E mpe |
| Qetello | E lumellana le Maemo a Khoebo | |
Litlamorao tse kholo tsa Sinomenine Hydrochloride li kenyelletsa:
(1) Anti-inflammatory: E fokotsa ho ruruha.
(2) Analgesic: E fana ka phomolo ea bohloko.
(3) Immunosuppressive: E hatella ts'ebetso ea sesole sa 'mele.
(4) Anti-rheumatic: E phekola ramatiki ea lefuba.
(5) Neuroprotective: E sireletsa lisele tsa methapo hore li se ke tsa senyeha.
(6) Anti-fibrotic: E thibela kapa e fokotsa fibrosis ea lisele.
Sinomenine Hydrochloride e sebelisoa haholo-holo libakeng tse latelang:
(1) Rheumatology: Kalafo ea ramatiki ea lefuba.
(2) Tlhokomelo ea Bohloko: Ho fokotsa bohloko bo sa foleng.
(3) Anti-inflammatory: Phokotso ea ho ruruha.
(4) Immunomodulation: Ho feto-fetoha ha tsamaiso ea 'mele ea ho itšireletsa mafung.
(5) Neuroprotection: Tšebeliso e ka 'nang ea e-ba teng ho li-neuroprotective therapies.
Ts'ebetso ea tlhahiso ea Sinomenine Hydrochloride Powder e ka akaretsoa ka tsela e latelang:
Tokisetso ea Litlama:Ho hloekisa le ho omisa thepa ea semela e tala.
Ho ntšoa:Ho sebelisa metsoako e kang ethanol ho ntša sinomenine semeleng sa semela.
Tsepamiso ea maikutlo:Ho etsa mouoane motsoako ho tsepamisa mohopolo oa sinomenine.
Alkalization:Ho fetola pH ho fetolela sinomenine ho sebopeho sa eona sa letsoai.
Mokelikeli oa Mokelikeli:Ho hloekisa ka li-solvents tse kang anisole kapa 1-heptanol.
Ho hlatsoa:Ho hlatsoa ka metsi ho tlosa litšila le mesaletsa ea mokelikeli.
Acidization:Ho fokotsa pH ho fokotsa sinomenine hydrochloride.
Crystallization:Ho etsa likristale tsa sinomenine hydrochloride.
Karohano:Centrifuging kapa sefa ho arola likristale ho tsoa ho tharollo.
Ho omisa:Ho tlosa mongobo o setseng ho likristale.
Ho sila:Ho sila likristale tse omisitsoeng ka phofo e ntle.
Sieving:Ho netefatsa kabo ea boholo ba likaroloana tse tšoanang.
Taolo ea Boleng:Teko ea ho hloeka, ho tsepamisa maikutlo, le litekanyetso tsa microbiological.
Sephutheloana:Sephutheloana se hloekileng le se sireletsehileng bakeng sa ho ajoa.
Polokelo: Boloka sebakeng se phodileng, se omileng, se hlwekileng, Sireletsa mongobong le leseding le otlolohileng.
Pakete e ngata: 25kg / moropa.
Nako ea ho etella pele: Matsatsi a 7 ka mor'a taelo ea hau.
Shelf Life: lilemo tse 2.
Tlhokomeliso: Litlhaloso tse ikhethileng le tsona li ka finyelloa.
Express
Ka tlase ho 100kg, matsatsi a 3-5
Tšebeletso ea ntlo le ntlo e bonolo ho nka thepa
Ka Leoatle
Ho feta 300kg, Hoo e ka bang Matsatsi a 30
Kou ho isa litšebeletsong tsa boema-kepe hoa hlokahala
Ka Moea
100kg-1000kg, 5-7Matsatsi
Boema-fofane ho ea litšebeletsong tsa boema-fofane ho hlokahala morekisi oa tumello ea litsebi
Bioway Organic e fumane litifikeiti tsa USDA le EU organic, BRC, ISO, HALAL, KOSHER, le HACCP.
