Corydalis Extract Tetrahydropalmatine (dl-THP)
Tetrahydropalmatine (THP), e tsejoang hape e le dl-THP, Corydalin hydrochloride, kapa Corydalin Tube Extract, ke motsoako o khethiloeng e le isoquinoline alkaloid. E ntšoa ho tuber ea setlama sa Sechaena Corydalis yanhusuo. THP ke ntho e se nang 'mala kapa e mosehla o mosehla e nang le tatso e babang hanyane le ntlha ea ho qhibiliha ea 147-149°C. Ha e qhibilihe ka metsing empa e qhibiliha haholo ho ether, chloroform le ethanol. Matsoai a eona a hydrochloride le sulfate a qhibiliha ka metsing.
THP e ithutiloe bakeng sa litlamorao tse fapaneng tsa meriana, ho kenyeletsoa le thepa ea eona ea ho kokobetsa bohloko, ho kokobetsa bohloko, ho sireletsa methapo, ho bokellana ha liplatelete, ho thibela seso, ho thibela hlahala le ho thibela bokhoba. Ho lumeloa hore e na le litlamorao tsa eona tsa ho kokobetsa bohloko ka ho fetola ts'ebetso ea receptor ea dopamine e bohareng 'me e bontšitse bokhoni ba ho sireletsa li-neurone ho tsoa kotsi ea ischemic. Ho feta moo, THP e bontšitse litlamorao tsa ho bokellana ha liplatelete 'me e fuputsoe ka bokhoni ba eona ba ho phekola liso, ho thibela kholo ea lisele tsa hlahala, le ho thusa bokhoba ba lithethefatsi.
Ka kakaretso, Tetrahydropalmatine (dl-THP) ke motsoako o nang le thepa e fapaneng ea meriana 'me e bile taba ea lipatlisiso tse pharaletseng bakeng sa lits'ebetso tsa eona tse ka bang teng tsa kalafo. Bakeng sa tlhaiso-leseling e batsi ikopanye le ronagrace@biowaycn.com.
Tsena ke likarolo tsa sehlahisoa sa Tetrahydropalmatine (THP) hammoho le melemo ea tsona ea bophelo bo botle:
1. Litšobotsi tsa ho Hlaba Bohloko:THP e bonts'a litlamorao tsa ho kokobetsa bohloko ka ho fetola ts'ebetso ea li-receptor tsa dopamine tse bohareng, e fanang ka phomolo ea bohloko ntle le bokhoni bo boholo ba ho lemalla.
2. Litlamorao tsa ho Sireletsa Methapo ea Kelello:THP e bontšitse bokhoni ba ho sireletsa li-neurone ho tsoa kotsi ea ischemic, ho fokotsa ho apoptosis ha li-neuron, le ho fokotsa maemo a glutamate bokong, e leng se ka tlatsetsang litšobotsing tsa eona tsa tšireletso ea li-neuron.
3. Ho Kopana ha Li-platelet:Ho fumanoe hore THP e thibela ho kopana ha li-platelet, e leng se ka fokotsang kotsi ea ho thehoa ha mali a thibaneng le liketsahalo tse amanang le pelo le methapo ea mali.
4. Tšehetso ea Bophelo bo Botle ba Mala:THP e bontšitse litlamorao tsa ho loantša liso 'me e ka thusa ho fokotsa ho ntšoa ha asiti ea ka mpeng, e fanang ka phomolo ho liso tsa ka mpeng le maemo a amanang le eona.
5. Mosebetsi o ka 'nang oa E-ba Teng oa ho Loantša Hlahala:THP e bontšitse litlamorao tsa chefo liseleng tsa hlahala, e leng se bontšang karolo e ka bang teng ho thibeleng kholo ea hlahala.
6. Litšobotsi tsa ho Loantša Bokhoba:THP e ithutiloe ka bokhoni ba eona ba ho fokotsa matšoao a ho khaotsa ho sebelisa opioid le bokhoba ba ho susumetsa, e fana ka tšepiso ea kalafo ea bokhoba le thibelo ea ho khutlela bokhobeng.
Likarolo tsena li totobatsa melemo e fapaneng ea bophelo bo botle le lits'ebetso tse ka bang teng tsa kalafo tsa Tetrahydropalmatine (THP).
Tetrahydropydalin (dl-THP) ke ea li-alkaloid tsa isoquinoline 'me ke alkaloid, haholo-holo mofuteng oa Corydalis lucidum (Yan Hu Suo), empa hape le limela tse ling tse kang Stephania rotunda. Limela tsena li na le tšebeliso ea setso merianeng ea litlama ea Chaena.Corydalis ke semela sa dimela se sa feleng, se bolelele ba 10 ho isa ho 20 cm, se nang le di-tuber tse chitja. Dikutu tsa sona tse ka hodimo ho lefatshe di kgutshwane ebile di tshesane, di na le sekala ka hodima motheo. Makhasi a tlase le makhasi a cauline a tshwana ka sebopeho, a na le dikutu; makhasi a cauline a fapanyetsana, a na le makhasi a 2 le a 3 a kopaneng. Lekhasi la bobedi hangata le petsoha ka ho feletseng mme le na le mahlakore a tebileng. Makhasi a manyane a malelele, a oval, kapa a oval. A otlolohileng, a bolelele ba 2 cm, a na le ntlha e sa hlakang kapa e bohale le mahlakore a matle. Palesa ya yona e bōpehile jwalo ka raceme, e na le makhasi a ho qetela kapa a shebaneng; di-bract di na le lanceolate ka bophara; dipalesa di kgubedu-pherese mme di hola ka ho rapama hodima di-pedicel tse tshesane, tse bolelele ba 6 mm; calyx e wa kapele; mahlaku a 4 mme di-whorl tse ka ntle ke 2 Dikarolo di kholoanyane hanyane, ka mahlakore a pinki le bohareng bo boputswa-pherese. Ho na le karolo e le nngwe e ka hodimo, mme mohatla o atoloha ho ba spur e telele. Bolelele ba spur bo etsa hoo e ka bang halofo ya bolelele bohle. Likarolo tse peli tse ka hare li tšesaane ho feta likarolo tse peli tse ka ntle. Karolo e ka holimo e putsoa-pherese 'me e folile, 'me karolo e ka tlase e pinki; Li-stamens li 6, 'me likhoele li hokahane ka lihlopha tse peli, e 'ngoe le e 'ngoe e na le li-anther tse 3; ovary e bataletse-cylindrical, setaele se sekhutšoanyane ebile se tšesaane, 'me stigma ke tse 2, joalo ka serurubele se senyenyane. Litholoana tsa eona ke capsule. Corydalis e hlahisoa haholo-holo lithabeng kapa makhulong. Libaka tse ka sehloohong tse hlahisang li kenyelletsa Zhejiang, Hebei, Shandong, Jiangsu le libaka tse ling.
| Tlhahlobo | Tlhaloso |
| Teko | Tetrahydropalmatine ≥98% |
| Ponahalo | Phofo e mosehla o bobebe ho isa ho e tšoeu |
| Molora | ≤0.5% |
| Mongobo | ≤5.0% |
| Libolaya-likokoana-hloko | Tse mpe |
| Litšepe tse boima | ≤10ppm |
| Pb | ≤2.0ppm |
| As | ≤2.0ppm |
| Monko o mobe | Tšobotsi |
| Boholo ba likaroloana | 100% ho isa ho 80 letlooeng |
| Likokoana-hloko: | |
| Kakaretso ea libaktheria | ≤1000cfu/g |
| Li-fungus | ≤100cfu/g |
| Salmgosella | Tse mpe |
| Coli | Tse mpe |
Mona ke liindasteri tsa ts'ebeliso ea lihlahisoa tsa Tetrahydropalmatine (THP):
1. Meriana:THP e sebelisoa indastering ea meriana bakeng sa ho nts'etsapele meriana ea taolo ea bohloko le meriana e sireletsang methapo.
2. Lijo tse matlafatsang:THP e sebelisoa indastering ea phepo e nepahetseng bakeng sa ho etsa li-supplement tse shebaneng le phomolo ea bohloko le tšehetso ea bophelo bo botle ba mpa.
3. Biotechnology:THP e fumana lits'ebetso theknolojing ea baeloji bakeng sa lipatlisiso mabapi le mekhoa ea phekolo ea antiplatelet le litlatsetso tse ka bang teng kalafong ea kankere.
4. Tlhokomelo ea Bophelo:THP e kenyelelitsoe dihlahisweng tsa tlhokomelo ya bophelo bakeng sa ho laola bokhoba le matshwao a ho tlohela a amanang le tshebediso ya opioid le di-stimulant.
5. Litlolo:THP e hlahlojoa ka har'a litlolo bakeng sa ts'ebeliso e ka bang teng ea bophelo bo botle ba letlalo le ho thibela ho ruruha.
Liindasteri tsena li bontša mekhoa e fapaneng ea ho sebelisa Tetrahydropalmatine (THP) maemong a fapaneng a nts'etsopele ea lihlahisoa le lipatlisiso.
Lihlahisoa tsa rona li etsoa ka ho sebelisa mehato e thata ea taolo ea boleng 'me li latela maemo a holimo a lits'ebetso tsa tlhahiso. Re beha polokeho le boleng ba sehlahisoa sa rona pele, re netefatsa hore se fihlela litlhoko tsa taolo le litifikeiti tsa indasteri. Boitlamo bona ba boleng bo ikemiselitse ho theha tšepo le kholiseho ho ts'epahaleng ha sehlahisoa sa rona. Ts'ebetso e akaretsang ea tlhahiso ke e latelang:
Polokelo:Boloka sebakeng se pholileng, se omileng le se hloekileng, Sireletsa mongobo le khanya e tobileng.
Sephutheloana se Seholo:20~25kg/moropa.
Lead time:Matsatsi a 7 kamora odara ea hau.
Bophelo ba Shelofo:lilemo tse 2.
Tlhaloso:Litlhaloso tse ikhethileng li ka finyelloa.
Hlahisa
Ka tlase ho 100kg, Matsatsi a 3-5
Tšebeletso ea ntlo le ntlo e bonolo ho e lata
Ka Leoatleng
Ho feta 300kg, Matsatsi a ka bang 30
Ho hlokahala morekisi oa tumello ea litsebi tsa koung ho tloha koung ho ea koung
Ka Moyeng
100kg-1000kg, Matsatsi a 5-7
Ho hlokahala morekisi oa litsebi oa tumello ea litšebeletso tsa boema-fofane ho tloha boema-fofaneng ho ea boema-fofaneng
Bioway e fumana mangolo a tumello a kang mangolo a USDA le a EU a tlhaho, mangolo a tumello a BRC, mangolo a tumello a ISO, mangolo a tumello a HALAL, le mangolo a tumello a KOSHER.
