Phepelo ea Feme e Hloekileng ea β-Nicotinamide adenine dinucleotide (NAD)
β-Nicotinamide adenine dinucleotide (NAD) ke coenzyme e fumanehang liseleng tsohle tse phelang, e bapala karolo ea bohlokoa lits'ebetsong tse fapaneng tsa metabolism. E bohlokoa bakeng sa tlhahiso ea matla, tokiso ea DNA, le pontšo ea lisele. NAD e teng ka mefuta e 'meli: NAD+ le NADH, tse amehang karabelong ea redox, ho fetisa lielektrone nakong ea mekhoa ea metabolic. NAD e bohlokoa bakeng sa ho boloka tšebetso ea lisele le bophelo bo botle ka kakaretso, mme maemo a eona a ka ama lits'ebetso tse fapaneng tsa 'mele. E sebelisoa haholo indastering ea meriana, biotechnology le lijo, hammoho le tlhahiso ea li-supplement le lijo tse sebetsang tse lebisitseng metabolism ea matla le bophelo bo botle ba liselefouno. Sebakeng sa feme, NAD e ka hlahisoa ka ho belisoa, ho sebelisa likokoana-hloko ho fetolela limolek'hule tsa pele ho NAD. Ts'ebetso ea tlhahiso e kenyelletsa taolo e hlokolosi ea maemo a belisoa ho ntlafatsa phetoho ea li-precursors ho NAD.
| Ntho | Boleng |
| Nomoro ea CAS. | 53-84-9 |
| Mabitso a Mang | beta-Nicotinamide adenine dinucleotide |
| MF | C21H27N7O14P2 |
| Nomoro ea EINECS | 200-184-4 |
| Sebaka sa Tšimoloho | China |
| Mofuta | Agrochemical Intermediates, Dyestuff Intermediates, Flavour & Monko o monate, Syntheses Material Intermediates |
| Bohloeki | 99% |
| Kopo | Syntheses Material Intermediates |
| Ponahalo | Phofo e tšoeu |
| Lebitso | beta-Nicotinamide adenine dinucleotide |
| MW | 663.43 |
| MF | C21H27N7O14P2 |
| Sebopeho | Tiileng |
| Ponahalo | Phofo e tšoeu |
| MOQ | 1kg |
| Mehlala | E fumaneha |
| Shelf Life | lilemo tse 2 |
Bohloeki bo Phahameng:NAD ea rona e hlahisoa ka mekhoa e tsoetseng pele ea tlhahiso ho netefatsa bohloeki bo phahameng, ho fihlela litekanyetso tse thata tse hlokahalang bakeng sa tšebeliso ea meriana, biotechnology le lijo.
Boleng bo Tletseng:Re boloka mehato e tiileng ea taolo ea boleng nakong eohle ea ts'ebetso ea tlhahiso ho netefatsa hore lihlahisoa tsa rona tsa NAD li lula li fihlela litekanyetso tse hlokahalang le maemo a ts'ebetso.
Lisebelisoa tse fapaneng:NAD ea rona e ka sebelisoa lits'ebetsong tse fapaneng tse fapaneng, ho kenyeletsoa meriana, litlatsetso tsa lijo, lijo tse sebetsang, le lits'ebetso tsa biotechnological, ka lebaka la karolo ea eona ea bohlokoa ho metabolism ea cellular le tlhahiso ea matla.
Tumellano ea Taolo:Lihlahisoa tsa rona tsa NAD li ikamahanya le maemo a tsamaiso ea machaba, ho netefatsa hore ho latela litataiso le melaoana e nepahetseng bakeng sa polokeho le boleng.
Phepelo e Tšepahalang:Re na le bokhoni ba tlhahiso le bokhoni ba ho fana ka phepelo e tšepahalang le e tsitsitseng ea NAD ho fihlela litlhoko tsa bareki ba rona.
Tšehetso ea tekheniki:Sehlopha sa rona sa litsebi se ka fana ka tšehetso ea tekheniki le tataiso mabapi le ho sebelisa NAD lits'ebetsong tse fapaneng, ho netefatsa hore bareki ba rona ba ka eketsa melemo ea lihlahisoa tsa rona.
Ka kakaretso, lihlahisoa tsa rona tsa NAD li khetholloa ka bohloeki ba tsona bo phahameng, boleng bo tsitsitseng, ho feto-fetoha ha maemo, ho latela melao, phepelo e tšepahalang, le ts'ehetso e felletseng ea tekheniki, e li etsang tse loketseng lits'ebetso tse fapaneng tsa indasteri le tsa khoebo.
β-Nicotinamide adenine dinucleotide (NAD) e hloekileng e fana ka mesebetsi e mengata le melemo e ka bang teng ea bophelo bo botle, ho kenyelletsa:
Tlhahiso ea Matla:
NAD e bapala karolo ea bohlokoa tlhahisong ea adenosine triphosphate (ATP), chelete ea mantlha ea matla a sele. Ka ho nka karolo ho karabelo ea redox, NAD e thusa phetiso ea lielektrone ts'ebetsong ea phosphorylation ea oxidative, e leng bohlokoa bakeng sa ho hlahisa ATP ho mitochondria.
Metabolism ea Mehala:
NAD e ameha mekhoeng e fapaneng ea metabolism, ho kenyelletsa glycolysis, tricarboxylic acid (TCA) cycle, le fatty acid oxidation. Mekhoa ena e bohlokoa bakeng sa ho senyeha le ho sebelisoa ha limatlafatsi bakeng sa tlhahiso ea matla le tšebetso ea lisele.
Tokiso ea DNA:
NAD ke motsoako oa li-enzyme tse amehang lits'ebetsong tsa tokiso ea DNA, joalo ka poly(ADP-ribose) polymerases (PARPs) le sirtuin. Li-enzyme tsena li bapala karolo ea bohlokoa ho boloka botsitso ba genomic le ho lokisa tšenyo ea DNA e bakiloeng ke khatello ea maikutlo e fapaneng.
Letšoao la Lisele:
NAD e sebetsa e le setsi sa li-sirtuin, sehlopha sa liprotheine tse amehang ho laoleng lits'ebetso tsa cellular joalo ka liphatsa tsa lefutso, apoptosis le karabelo ea khatello ea maikutlo. Li-Sirtuins li ameha ka nako e telele 'me li amahanngoa le melemo ea bophelo bo botle.
Melemo e ka bang teng ea Bophelo bo Botle:
Lipatlisiso li fana ka maikutlo a hore tlatsetso ea NAD kapa ho feto-fetoha ha maemo a NAD ho ka ba le melemo ea bophelo bo botle, ho kenyeletsoa ho ts'ehetsa ts'ebetso ea mitochondrial, ho khothaletsa botsofali bo botle, le maemo a ka bang a ama a amanang le ho se sebetse hantle ha metabolic le khatello ea maikutlo.
β-Nicotinamide adenine dinucleotide (NAD) e hloekileng e na le lisebelisoa tse ngata ho pholletsa le liindasteri tse fapaneng ka lebaka la karolo ea eona ea bohlokoa metabolism ea lisele le tlhahiso ea matla. Tse ling tsa lits'ebetso tsa bohlokoa tsa NAD e hloekileng li kenyelletsa:
Indasteri ea Litlhare:
NAD e sebelisoa e le karolo ea bohlokoa mekhoeng ea meriana, haholo-holo meriana e shebaneng le mathata a metabolism, ho se sebetse ha mitochondrial, le maemo a amanang le lilemo. E boetse e sebelisoa ho etsa lipatlisiso le nts'etsopele bakeng sa mehato e ka bang teng ea phekolo.
Lisebelisoa tsa Lijo:
NAD e kenyelelitsoe ho li-supplement tsa lijo tse reretsoeng ho ts'ehetsa bophelo bo botle ba lisele, metabolism ea matla, le bophelo bo botle ka kakaretso. Li-supplement tsena li rekisoa bakeng sa bokhoni ba tsona ba ho khothaletsa botsofali bo botle le ts'ebetso ea metabolism.
Lijo le lino tse Sebetsang:
NAD e sebelisoa ho nts'etsopele ea lijo le lino tse sebetsang hantle tse etselitsoeng ho ts'ehetsa tlhahiso ea matla, bophelo bo botle ba liselefouno le ho leka-lekana ha metabolism. Lihlahisoa tsena li ka lebisa bareki ba batlang mekhoa ea tlhaho ea ho ntlafatsa bophelo bo botle le matla a bona.
Biotechnology:
NAD e sebelisoa lits'ebetsong tse fapaneng tsa biotechnology, ho kenyelletsa setso sa lisele, ho belisoa, le boenjiniere ba enzyme. E sebetsa e le cofactor ea bohlokoa liketsong tse ngata tsa enzymatic le litsela tsa metabolic, e etsa hore e be ea bohlokoa ho bioprocessing le biomanufacturing.
Lipatlisiso le Ntlafatso:
NAD e sebelisoa e le sesebelisoa sa ho etsa lipatlisiso lilaboratoring tsa thuto le tsa indasteri ho ithuta metabolism ea cellular, tlhahiso ea matla, le melemo e ka bang teng ea bophelo bo botle e amanang le ho feto-fetoha ha molumo oa NAD. Hape ke taba ea lipatlisiso tsa mahlale mabapi le litlamorao tsa eona botsofaling, mafu a metabolism le maemo a neurodegenerative.
Cosmeceuticals:
NAD e kenyelelitsoe ho skincare le lihlahisoa tsa litlolo bakeng sa bokhoni ba eona ba ho ts'ehetsa bophelo bo botle ba lisele le mahlahahlaha. E rekisoa e le motsoako o thibelang botsofali le thepa ea ho tsosolosa.
Sehlahisoa sa rona se thehiloeng ho limela se etsoa ho sebelisoa mehato e thata ea ho laola boleng 'me e khomarela litekanyetso tse phahameng tsa mekhoa ea tlhahiso. Re etelletsa pele polokeho le boleng ba sehlahisoa sa rona, ho netefatsa hore se fihlela litlhoko tsa taolo le litifikeiti tsa indasteri. Boitlamo bona ba boleng bo ikemiselitse ho theha ts'epo le ts'epo ea ho ts'epahala ha sehlahisoa sa rona. Mokhoa o akaretsang oa tlhahiso ke o latelang:
Polokelo: Boloka sebakeng se phodileng, se omileng, se hlwekileng, Sireletsa mongobong le leseding le otlolohileng.
Pakete e ngata: 25kg / moropa.
Nako ea ho etella pele: Matsatsi a 7 ka mor'a taelo ea hau.
Shelf Life: lilemo tse 2.
Tlhokomeliso: Litlhaloso tse ikhethileng le tsona li ka finyelloa.
25kg / nyeoe
Sephutheloana se matlafalitsoeng
Tšireletso ea thepa
Express
Ka tlase ho 100kg, matsatsi a 3-5
Tšebeletso ea ntlo le ntlo e bonolo ho nka thepa
Ka Leoatle
Ho feta 300kg, Hoo e ka bang Matsatsi a 30
Kou ho isa litšebeletsong tsa boema-kepe hoa hlokahala
Ka Moea
100kg-1000kg, 5-7Matsatsi
Boema-fofane ho ea litšebeletsong tsa boema-fofane ho hlokahala morekisi oa tumello ea litsebi
Bioway e fumana litifikeiti tse kang USDA le litifikeiti tsa organic tsa EU, litifikeiti tsa BRC, litifikeiti tsa ISO, litifikeiti tsa HALAL, le litifikeiti tsa KOSHER.
