Vinca Rosea Extract Vincristine
Vinca Rosea Extract Vincristine e bua ka motsoako oa meriana Vincristine, o nkiloeng ho semela sa periwinkle (Vinca rosea), se tsejoang hape e le Catharanthus roseus, mahlo a khanyang, Cape periwinkle, semela sa mabitla, Madagascar periwinkle, lekhabunyane la khale, periwinkle e pinki, rose. periwinkle, ke mofuta o sa feleng oa semela se thunyang sa lelapa la Apocynaceae.
Vincristine ke alkaloid ea tlhaho 'me e sebelisoa e le meriana ea chemotherapy ho phekola mefuta e sa tšoaneng ea kankere, ho akarelletsa leukemia, lymphoma, le lihlahala tse tiileng.E sebetsa ka ho sitisa kholo ea lisele tsa mofetše.
| Lisebelisoa tse ka sehloohong tse sebetsang ka Sechaena | Lebitso la Senyesemane | Nomoro ea CAS. | Boima ba Molek'hule | Foromo ea limolek'hule |
| 长春胺 | Vincamine | 1617-90-9 | 354.44 | Setšoantšo sa C21H26N2O3 |
| 脱水长春碱 | Anhydrovinblastine | 38390-45-3 | 792.96 | Setšoantšo sa C46H56N4O8 |
| 異長春花苷內酰胺 | Strictosamide | 23141-25-5 | 498.53 | C26H30N2O8 |
| 四氢鸭脚木碱 | Tetrahydroalstonine | 6474-90-4 | 352.43 | C21H24N2O3 |
| 酒石酸长春瑞滨 | Vinorelbine tartrate | 125317-39-7 | 1079.12 | C45H54N4O8.2(C4H6O6);C |
| 长春瑞滨 | Vinorelbine | 71486-22-1 | 778.93 | Setšoantšo sa C45H54N4O8 |
| 长春新碱 | Vincristine | 57-22-7 | 824.96 | Setšoantšo sa C46H56N4O10 |
| 硫酸长春新碱 | Vincristine sulfate | 2068-78-2 | 923.04 | Setšoantšo sa C46H58N4O14S |
| 硫酸长春质碱 | Catharanthine sulfate | 70674-90-7 | 434.51 | Setšoantšo sa C21H26N2O6S |
| 酒石酸长春质碱 | Catharanthine hemitartrate | 4168-17-6 | 486.51 | C21H24N2O2.C4H6O6 |
| 长春花碱 | Vinblastine | 865-21-4 | 810.99 | Setšoantšo sa C46H58N4O9 |
| 长春质碱 | Catharanthine | 2468-21-5 | 336.43 | Setšoantšo sa C21H24N2O2 |
| 文朵灵 | Vindoline | 2182-14-1 | 456.53 | C25H32N2O6 |
| 硫酸长春碱 | Vinblastine sulfate | 143-67-9 | 909.05 | Setšoantšo sa C46H60N4O13S |
| β-谷甾醇 | β-Sitosterol | 83-46-5 | 414.71 | C29H50O |
| 菜油甾醇 | Campesterol | 474-62-4 | 400.68 | C28H48O |
| 齐墩果酸 | Oleanolic acid | 508-02-1 | 456.7 | C30H48O3 |
| TLHOKOMELO SEHLABAKA | ||
| Lebitso la Sehlahisoa: | Vinca rosea e nepahetseng | |
| Lebitso la Botanic: | Catharanthus roseus (L.) | |
| Karolo ea semela | Palesa | |
| Naha ea tlhaho: | China | |
| TLHOKOMELO NTHO | TS'ELISO | TEKO MOKHOA |
| Ponahalo | Phofo e ntle | Organoleptic |
| Mmala | Phofo e ntle e sootho | E bonoang |
| Monko & Tatso | Sebopeho | Organoleptic |
| Boitsebiso | E ts'oana le sampole ea RS | HPTLC |
| Karolelano ea Ntša | 4:1–20:1;Vincristine 98%min | |
| Sieve Analysis | 100% ho isa ho 80 mesh | USP39 <786> |
| Tahlehelo ka ho omisa | ≤ 5.0% | Eur.Ph.9.0 [2.5.12] |
| Kakaretso ea Molora | ≤ 5.0% | Eur.Ph.9.0 [2.4.16] |
| Ketapele (Pb) | ≤ 3.0 mg/kg | Eur.Ph.9.0<2.2.58>ICP-MS |
| Arsenic (As) | ≤ 1.0 mg/kg | Eur.Ph.9.0<2.2.58>ICP-MS |
| Cadmium(Cd) | ≤ 1.0 mg/kg | Eur.Ph.9.0<2.2.58>ICP-MS |
| Mercury(Hg) | ≤ 0.1 mg / kg -Reg.EC629/2008 | Eur.Ph.9.0<2.2.58>ICP-MS |
| Tšepe e boima | ≤ 10.0 mg/kg | Eur.Ph.9.0<2.4.8> |
| Masala a Li-solvents | E lumellana le Eur.ph.9.0 <5,4 > le EC European Directive 2009/32 | Eur.Ph.9.0<2.4.24> |
| Masala a chefo e bolaeang likokoanyana | Conform Regulations(EC) No.396/2005ho kenyeletsoa lihlomathiso le lintlafatso tse latellanang Reg.2008/839/CE | Chromatography ea Khase |
| Libaktheria tsa Aerobic (TAMC) | ≤10000 cfu/g | USP39 <61> |
| Yeast/Mould(TAMC) | ≤1000 cfu/g | USP39 <61> |
| Escherichia coli: | Ha e eo ka 1g | USP39 <62> |
| Salmonella spp: | Ha e eo ka 25g | USP39 <62> |
| Staphylococcus aureus: | Ha e eo ka 1g | |
| Listeria Monocytogenens | Ha e eo ka 25g | |
| Aflatoxins B1 | ≤ 5 ppb -Reg.EC 1881/2006 | USP39 <62> |
| Aflatoxins ∑ B1, B2, G1, G2 | ≤ 10 ppb -Reg.EC 1881/2006 | USP39 <62> |
Likarolo tsa sehlahisoa sa Vinca Rosea Extract Vincristine li ka kenyelletsa:
Bohloeki bo phahameng:Hangata lihlahisoa tsa Vincristine li na le bohloeki bo phahameng 'me li lumellana le litekanyetso tse tiileng tsa ho etsa lithethefatsi ho netefatsa bohloeki le botsitso ba lithethefatsi.
Mohloli oa traceability:Vincristine hangata e ntšoa semela sa Catharanthus roseus.Ts'ebetso ea eona ea tlhahiso ea fumaneha hape e lumellana le litlhaloso tsa pokello le tlhahiso ea lisebelisoa tsa bongaka tsa botanical.
Ho tsitsa ha lik'hemik'hale:Joaloka motsoako oa alkaloid, vincristine e na le botsitso bo botle ba lik'hemik'hale 'me e loketse tlhahiso ea meriana le polokelo ea nako e telele.
Mosebetsi oa anti-tumor:Joaloka lithethefatsi tse khahlanong le hlahala, vincristine e na le mosebetsi oa ho thibela ho hōla le ho ata ha lisele tsa hlahala 'me e loketse phekolo ea mefuta e sa tšoaneng ea kankere.
Netefatso ea bongaka:Vincristine e netefalitsoe ka bongaka mme e sebelisoa haholo mekhoeng ea bongaka, e nang le ts'ehetso ea data e tšepahalang ea pharmacological le ea kliniki.
Litšobotsi tsena tsa sehlahisoa li totobatsa boleng, tšebetso, le boleng ba bongaka ba vincristine e le setlhare sa bohlokoa se thibelang mofetše.
Vinca Rosea Extract Vincristine e tsebahala haholo ka ts'ebeliso ea eona ea meriana kalafong ea mofets'e mme hangata ha e amane le melemo ea bophelo bo botle bakeng sa tšebeliso e akaretsang ea bareki.Vincristine, e nkiloeng semeleng sa Vinca rosea, ke moriana o matla oa chemotherapy o sebelisoang ho alafa mefuta e fapaneng ea mofetše, ho kenyelletsa leukemia, lymphoma le lihlahala tse tiileng.E sebetsa ka ho sitisa kholo ea lisele tsa mofetše.
Ke habohlokoa ho hlokomela hore Vincristine ke meriana e fanoang ke ngaka e tsamaisoang tlas'a tlhokomelo ea litsebi tsa bophelo bo botle, 'me tšebeliso ea eona e amahanngoa le litla-morao le likotsi tse ka bang teng.Ka hona, hangata ha e rekisoe kapa ho jeoa bakeng sa melemo ea eona ea bophelo bo botle kantle ho maemo a kliniki.
Lisebelisoa tse qaqileng tsa Vinca Rosea Extract Vincristine li kenyelletsa:
Kalafo ea Mofets'e:Vincristine e sebelisoa haholo-holo ho phekola mefuta e sa tšoaneng ea kankere, ho akarelletsa leukemia, lymphoma, le lihlahala tse tiileng.E tsamaisoa e le karolo ea chemotherapy regimens ho thibela kholo ea lisele tsa mofetše.
Patlisiso ea Meriana:Motsoako ona o sebelisoa lipatlisisong tsa meriana bakeng sa nts'etsopele ea kalafo e ncha ea mofets'e le boithuto ba mokhoa oa ts'ebetso ea ona.
Khemistri ea Meriana:Vincristine e sebetsa e le motsoako oa bohlokoa lefapheng la k'hemistri ea meriana, e tlatsetsang ho nts'etsopele ea lithethefatsi tse ncha le mekhoa ea phekolo.
Biotechnology:Motsoako ona o ka sebelisoa lits'ebetsong tsa biotechnological, joalo ka tlhahiso ea litlolo tse thibelang mofetše le litsamaiso tsa phepelo ea lithethefatsi.
Liteko tsa Clinical:Vincristine e kenya letsoho litekong tsa bongaka ho hlahloba katleho ea eona ea ho phekola mefuta e sa tšoaneng ea mofetše le ho batlisisa mekhoa e ka sebelisoang maemong a mang a bongaka.
Tlhahiso ea Lithethefatsi:Motsoako o sebelisoa ha ho etsoa lihlahisoa tsa meriana, ho kenyelletsa le tharollo e nang le ente le mefuta e meng ea litekanyetso bakeng sa kalafo ea mofets'e.
Lisebelisoa tsena li bonts'a ts'ebeliso e fapaneng ea Vinca Rosea Extract Vincristine kalafong ea mofetše, lipatlisiso tsa meriana le nts'etsopele ea lithethefatsi.
Vincristine ke meriana e matla ea chemotherapy, 'me tšebeliso ea eona e ka amahanngoa le litla-morao tse' maloa tse ka bang teng.Tse ling tsa litla-morao tse ka bang teng tsa phofo ea Vincristine li ka kenyelletsa:
Neurotoxicity:Vincristine e ka baka tšenyo tsamaisong ea methapo ea peripheral, e lebisang matšoao a kang ho tsieleha, ho tsikitlanya le ho fokola lipheletsong.
Liphello tsa Gastrointestinal:Litla-morao tse tloaelehileng tsa mala a ka mpeng li ka kenyelletsa ho nyekeloa ke pelo, ho hlatsa, ho patoa, le mahlaba ka mpeng.
Khatello ea Bone Marrow:Vincristine e ka hatella moko oa masapo, e leng se lebisang ho fokotseng tlhahiso ea lisele tsa mali, e leng se ka fellang ka khaello ea mali, ho ba le tšoaetso e eketsehileng ea tšoaetso, le tšekamelo ea ho tsoa mali.
Ho lahleheloa ke Moriri:Batho ba bang ba ka 'na ba lahleheloa ke moriri kapa ba fokotsa moriri ka lebaka la phekolo ea Vincristine.
Mahlaba a Mehlahare:Vincristine e ka baka mofuta o itseng oa bohloko bo tsejoang e le "vincristine-induced neuropathy-acute-onset," e khetholloang ke bohloko ba mohlahare le bothata ba ho metsa.
Liphello tse ling tse ka bang teng:Litla-morao tse ling li ka kenyelletsa ho fokola ha mesifa, liphetoho khatellong ea mali, le ho hana ho hana.
Ke habohlokoa ho hlokomela hore lenane le ka holimo ha le felle, 'me litsebi tsa tlhokomelo ea bophelo li lokela ho beha leihlo batho ba fumanang Vincristine bakeng sa litla-morao tse ka bang teng.Litla-morao tse khethehileng le ho teba ha tsona li ka fapana ho ea ka motho.Bakuli ba lokela ho buisana ka litla-morao tse ka 'nang tsa e-ba teng le mathata le mofani oa bona oa tlhokomelo ea bophelo pele ba qala kalafo ea Vincristine.
Packaging le Tšebeletso
Sephutheloana
* Nako ea Phano: Hoo e ka bang matsatsi a 3-5 a mosebetsi ka mor'a tefo ea hau.
* Pakete: Ka har'a meqomo ea fiber e nang le mekotla e 'meli ea polasetiki kahare.
* Net Weight: 25kgs/drum, Gross Weight: 28kgs/Drum
* Boholo ba Moropa le Bophahamo: ID42cm × H52cm, 0.08 m³/ Drum
* Polokelo: E bolokiloe sebakeng se omeletseng le se pholileng, qoba khanya e matla le mocheso.
* Shelf Life: Lilemo tse peli ha li bolokiloe hantle.
Ho tsamaisa ka sekepe
* DHL Express, FEDEX, le EMS bakeng sa bongata bo ka tlase ho 50KG, hangata e bitsoang ts'ebeletso ea DDU.
* Ho tsamaisoa ha leoatle ka bongata bo fetang 500 kg;'me sekepe sa moea se fumaneha bakeng sa lik'hilograma tse 50 holimo.
* Bakeng sa lihlahisoa tsa boleng bo holimo, ka kopo khetha ho tsamaisa moea le DHL Express bakeng sa polokeho.
* Ka kopo netefatsa hore na u ka etsa tumello ha thepa e fihla meetlong ea hau pele u etsa odara.Bakeng sa bareki ba tsoang Mexico, Turkey, Italy, Romania, Russia, le libakeng tse ling tse hole.
Tefo le Mekhoa ea Phano
Express
Ka tlase ho 100kg, Matsatsi a 3-5
Tšebeletso ea ntlo le ntlo e bonolo ho nka thepa
Ka Leoatleng
Ho feta 300kg, Hoo e ka bang Matsatsi a 30
Kou ho isa litšebeletsong tsa boema-kepe hoa hlokahala
Ka Moea
100kg-1000kg, Matsatsi a 5-7
Boema-fofane ho ea litšebeletsong tsa boema-fofane ho hlokahala morekisi oa tumello ea litsebi
Lintlha tsa Tlhahiso (Chate e Phallang)
1. Ho Fuma le ho Kotula
2. Ho ntšoa
3. Tsepamiso le Tlhoekiso
4. Ho omisa
5. Boemo ba maemo
6. Taolo ea Boleng
7. Packaging 8. Kabo
Setifikeiti
It e netefalitsoe ke litifikeiti tsa ISO, HALAL, le KOSHER.
