Melemo ea Ginsenosides ke efe?

Mosebetsi oa Kelello

E 'ngoe ea melemo e tsebahalang haholo ea li-ginsenosides ke bokhoni ba tsona ba ho ntlafatsa ts'ebetso ea kelello. Lithuto tse 'maloa li bontšitse hore li-ginsenosides li ka ntlafatsa mohopolo, ho ithuta le ts'ebetso ea kelello ka kakaretso. Litlamorao tsena ho nahanoa hore li tsamaisoa ke mekhoa e fapaneng, ho kenyeletsoa le ho fetoloa ha li-neurotransmitters, joalo ka acetylcholine le dopamine, le ho khothaletsa neurogenesis, ts'ebetso ea ho hlahisa li-neurone tse ncha bokong.

Phuputsong e phatlalalitsoeng ho Journal of Ethnopharmacology, bafuputsi ba fumane hore li-ginsenosides li ka ntlafatsa thuto ea sebaka le mohopolo ho litoeba ka ho ntlafatsa polelo ea neurotrophic factor (BDNF) e nkiloeng bokong, e leng protheine e tšehetsang ho phela le kholo ea li-neuron. Ho feta moo, li-ginsenosides li bontšitsoe li sireletsa khahlanong le ho fokotseha ha tsebo ho amanang le botsofali le mafu a neurodegenerative, joalo ka lefu la Alzheimer's le Parkinson's, ka ho fokotsa khatello ea oxidative le ho ruruha bokong.

Ho Fetola Tsamaiso ea 'Mele ea ho Itšireletsa

Ho boetse ho fumanoe hore li-ginsenoside li fetola sesole sa 'mele, li ntlafatsa bokhoni ba sona ba ho itšireletsa khahlanong le tšoaetso le mafu. Metsoako ena e bontšitsoe e susumetsa tlhahiso le ts'ebetso ea lisele tse fapaneng tsa 'mele, tse kang lisele tsa tlhaho tse bolaeang, macrophages le li-T lymphocyte, tse bapalang karolo ea bohlokoa tšireletsong ea 'mele khahlanong le likokoana-hloko le lisele tsa mofetše.

Phuputso e phatlalalitsoeng koranteng ea International Immunopharmacology e bontšitse hore li-ginsenosides li ka ntlafatsa karabelo ea 'mele ea ho itšireletsa mafung litoebeng ka ho eketsa tlhahiso ea li-cytokine, tse leng lipontšo tsa limolek'hule tse laolang ts'ebetso ea sele ea 'mele ea ho itšireletsa mafung. Ho feta moo, li-ginsenosides li bontšitsoe li na le thepa ea ho loantša vaerase le ea ho loantša baktheria, e leng se etsang hore e be pheko ea tlhaho e tšepisang bakeng sa ho tšehetsa bophelo bo botle ba 'mele ea ho itšireletsa mafung le ho thibela tšoaetso.

Matlotlo a Thibelang ho Ruruha

Ho ruruha ke karabelo ea tlhaho ea sesole sa 'mele ho tsoa kotsi le tšoaetso, empa ho ruruha ho sa foleng ho ka kenya letsoho ho holiseng mafu a fapaneng, ho kenyeletsoa lefu la pelo, lefu la tsoekere le kankere. Li-ginsenoside li fumanoe li na le thepa e matla ea ho thibela ho ruruha, e ka thusang ho fokotsa litlamorao tse kotsi tsa ho ruruha ho sa foleng 'meleng.

Phuputso e phatlalalitsoeng ho Journal of Ginseng Research e bontšitse hore li-ginsenoside li ka thibela tlhahiso ea li-cytokine tse bakang ho ruruha le ho thibela ts'ebetso ea litsela tsa matšoao a ho ruruha liseleng tsa 'mele. Ho feta moo, li-ginsenoside li bontšitsoe li fokotsa tlhahiso ea li-mediator tsa ho ruruha, tse kang cyclooxygenase-2 (COX-2) le inducible nitric oxide synthase (iNOS), tse amehang karabelong ea ho ruruha.

Mosebetsi oa ho Loantša Kankere

Karolo e 'ngoe e thahasellisang lipatlisisong tsa ginsenoside ke ts'ebetso ea tsona e ka bang teng khahlanong le mofetše. Lithuto tse 'maloa li bontšitse hore ginsenosides e ka ba le litlamorao khahlanong le mofetše ka ho thibela kholo le ho ata ha lisele tsa mofetše, e leng se bakang apoptosis (lefu la sele le hlophisitsoeng), le ho thibela angiogenesis ea hlahala (ho thehoa ha methapo e mecha ea mali ho tšehetsa kholo ea hlahala).

Tlhahlobo e phatlalalitsoeng ho International Journal of Molecular Sciences e totobalitse bokhoni ba li-ginsenosides khahlanong le kankere, haholo-holo mofetšeng oa matsoele, oa matšoafo, oa sebete le oa mala. Tlhahlobo e buisane ka mekhoa e fapaneng eo li-ginsenosides li sebelisang litlamorao tsa tsona khahlanong le kankere ka eona, ho kenyeletsoa le ho fetola litsela tsa lipontšo tsa sele, taolo ea tsoelo-pele ea potoloho ea sele, le ntlafatso ea karabelo ea 'mele ea ho itšireletsa mafung khahlanong le lisele tsa kankere.

Qetello

Qetellong, ginsenosides ke metsoako e sebetsang e fumanehang ho Panax ginseng e fanang ka melemo e mengata e ka bang teng bophelong. Tsena di kenyeletsa ntlafatso tshebetsong ya kelello, ho fetolwa ha sesole sa mmele, thepa ya ho thibela ho ruruha, le tshebetso e ka bang teng ya ho thibela kankere. Le hoja ho hlokahala dipatlisiso tse ding ho utlwisisa ka botlalo mekgwa ya tshebetso le bokgoni ba kalafo ba ginsenosides, bopaki bo teng bo bontsha hore metsoako ena e tshepisa e le pheko ya tlhaho bakeng sa ho kgothaletsa bophelo bo botle le boiketlo ka kakaretso.

Litšupiso
Kim, JH, & Yi, YS (2013). Ginsenoside Rg1 e thibela ho kenngwa tshebetsong ha disele tsa dendritic le ho ata ha disele tsa T ka hara mmele le ka hara mmele. International Immunopharmacology, 17(3), 355-362.
Leung, KW, & Wong, AS (2010). Pharmacology ea ginsenosides: tlhahlobo ea lingoliloeng. Bongaka ba Chaena, 5(1), 20.
Radad, K., Gille, G., Liu, L., Rausch, WD, & Tšebeliso ea ginseng meriana ka ho totobatsa mathata a methapo ea kutlo. Journal of Pharmacological Sciences, 100(3), 175-186.
Wang, Y., & Liu, J. (2010). Ginseng, leano le ka bang teng la ho sireletsa methapo. Bongaka bo Tlatsetsang le bo Bong bo Thehiloeng Bopaking, 2012.
Yun, TK (2001). Kenyelletso e khuts'oane ea Panax ginseng CA Meyer. Journal of Korean Medical Science, 16(Suppl), S3.