Melemo ea Ginsenosides ke efe?

Selelekela
Ginsenosideske sehlopha sa metsoako ea tlhaho e fumanoang metsong ea semela sa Panax ginseng, se 'nileng sa sebelisoa ka lilemo tse makholo meriana ea setso ea Sechaena. Lik'hemik'hale tsena tsa bioactive li fumane tlhokomelo e kholo lilemong tsa morao tjena ka lebaka la melemo ea tsona ea bophelo bo botle. Sehloohong sena, re tla hlahloba melemo e sa tšoaneng ea ginsenosides, ho kenyelletsa le liphello tsa bona mosebetsing oa kelello, ho feto-fetoha ha tsamaiso ea 'mele ea ho itšireletsa mafung, thepa e khahlanong le ho ruruha, le ts'ebetso e ka' nang ea e-ba khahlanong le kankere.

Mosebetsi oa Kelello

E 'ngoe ea melemo e tsebahalang haholo ea ginsenosides ke bokhoni ba bona ba ho ntlafatsa ts'ebetso ea kelello. Liphuputso tse 'maloa li bontšitse hore ginsenosides e ka ntlafatsa mohopolo, ho ithuta, le ts'ebetso ea kelello ka kakaretso. Liphello tsena ho nahanoa hore li fetisetsoa ka mekhoa e sa tšoaneng, ho kenyelletsa le ho feto-fetoha ha li-neurotransmitters, tse kang acetylcholine le dopamine, le ho khothalletsa neurogenesis, mokhoa oa ho hlahisa li-neurone tse ncha bokong.

Phuputsong e phatlalalitsoeng ho Journal of Ethnopharmacology, bafuputsi ba fumane hore ginsenosides e ka ntlafatsa thuto ea sebaka le mohopolo ho likhoto ka ho ntlafatsa polelo ea boko bo tsoang bokong ba neurotrophic factor (BDNF), protheine e tšehetsang ho phela le ho hōla ha methapo ea kutlo. Ho feta moo, li-ginsenosides li bonts'itsoe hore li sireletsa khahlanong le ho fokotseha ho amanang le botsofali le mafu a neurodegenerative, joalo ka lefu la Alzheimer's le Parkinson's, ka ho fokotsa khatello ea oxidative le ho ruruha bokong.

Ho Fetola ha Tsamaiso ea 'mele ea ho itšireletsa mafung

Li-ginsenosides li boetse li fumanoe li lekanya sesole sa 'mele, se matlafatsa bokhoni ba sona ba ho itšireletsa khahlanong le tšoaetso le mafu. Metsoako ena e bontšitsoe hore e susumetsa tlhahiso le tšebetso ea lisele tse fapaneng tsa 'mele tsa ho itšireletsa mafung, tse kang lisele tse bolaeang tsa tlhaho, macrophages le T lymphocyte, tse phethang karolo ea bohlokoa tšireletsong ea 'mele khahlanong le likokoana-hloko le lisele tsa mofetše.

Phuputso e phatlalalitsoeng koranteng ea International Immunopharmacology e bonts'itse hore ginsenosides e ka ntlafatsa karabelo ea 'mele ea ho itšireletsa mafung ho litoeba ka ho eketsa tlhahiso ea li-cytokine, e leng limolek'hule tse laolang tšebetso ea lisele tsa' mele. Ntle le moo, ginsenosides e bonts'itsoe hore e na le thepa ea antiviral le antibacterial, e e etsang hore e be pheko ea tlhaho e ts'episang ho ts'ehetsa bophelo bo botle ba 'mele le ho thibela tšoaetso.

Thepa e Khahlanong le ho Ruta

Ho ruruha ke karabelo ea tlhaho ea sesole sa 'mele ho tsoa kotsi le tšoaetso, empa ho ruruha ho sa foleng ho ka tlatsetsa ho nts'etsopele ea mafu a sa tšoaneng, ho akarelletsa le lefu la pelo, lefu la tsoekere le kankere. Ginsenosides e fumanoe e na le thepa e matla ea ho thibela ho ruruha, e ka thusang ho fokotsa litlamorao tse mpe tsa ho ruruha ho sa foleng 'meleng.

Phuputso e phatlalalitsoeng ho Journal of Ginseng Research e bonts'itse hore ginsenosides e ka hatella tlhahiso ea li-cytokine tse pro-inflammatory le ho thibela ts'ebetso ea matšoao a ho ruruha liseleng tsa 'mele. Ho phaella moo, li-ginsenosides li bontšitsoe ho fokotsa polelo ea bahlaseli ba ho ruruha, ba kang cyclooxygenase-2 (COX-2) le inducible nitric oxide synthase (iNOS), e amehang karabelong ea ho ruruha.

Mosebetsi oa Anticancer

Karolo e 'ngoe ea thahasello lipatlisisong tsa ginsenoside ke ts'ebetso ea bona e ka bang teng ea anticancer. Liphuputso tse 'maloa li bontšitse hore ginsenosides e ka ba le litlamorao tse khahlanong le mofets'e ka ho thibela kholo le ho ata ha lisele tsa mofets'e, ho baka apoptosis (ho shoa ha lisele tse hlophisitsoeng), le ho hatella tumor angiogenesis (ho theoa ha methapo e mecha ea mali ho tšehetsa kholo ea hlahala).

Tlhahlobo e hatisitsoeng ho International Journal of Molecular Sciences e totobalitse matla a anticancer a ginsenosides, haholo-holo mofetšeng oa matsoele, matšoafo, sebete le colorectal. Tlhahlobo e ile ea tšohla mekhoa e fapaneng eo ginsenosides e nang le litlamorao tsa eona tse khahlanong le mofets'e, ho kenyelletsa le ho feto-fetoha ha litsela tsa matšoao a lisele, taolo ea tsoelo-pele ea potoloho ea lisele, le ntlafatso ea karabelo ea 'mele ea ho itšireletsa mafung khahlano le lisele tsa mofetše.

Qetello

Qetellong, ginsenosides ke metsoako ea bioactive e fumanoang ho Panax ginseng e fanang ka mefuta e mengata ea melemo ea bophelo bo botle. Tsena li kenyelletsa ntlafatso ea ts'ebetso ea kelello, ho feto-fetoha ha tsamaiso ea 'mele ea ho itšireletsa mafung, thepa e khahlanong le ho ruruha, le ts'ebetso e ka bang teng ea ho thibela mofetše. Le hoja lipatlisiso tse eketsehileng li hlokahala ho utloisisa ka botlalo mekhoa ea ts'ebetso le phekolo ea phekolo ea ginsenosides, bopaki bo teng bo bontša hore metsoako ena e na le tšepiso e le litlhare tsa tlhaho bakeng sa ho khothalletsa bophelo bo botle le boiketlo ka kakaretso.

Litšupiso
Kim, JH, & Yi, YS (2013). Ginsenoside Rg1 e hatella ts'ebetso ea lisele tsa dendritic le T cell proliferation in vitro le in vivo. International Immunopharmacology, 17 (3), 355-362.
Leung, KW, & Wong, AS (2010). Pharmacology ea ginsenosides: tlhahlobo ea lingoliloeng. Meriana ea Machaena, 5(1), 20.
Radad, K., Gille, G., Liu, L., Rausch, WD, & Tšebeliso ea ginseng meriana ka ho hatisa mathata a neurodegenerative. Journal of Pharmacological Sciences, 100 (3), 175-186.
Wang, Y., & Liu, J. (2010). Ginseng, leano le ka bang teng la ho sireletsa methapo ea kutlo. Meriana e Tlatselletsang le e meng e Thehiloeng ho Bopaki, 2012.
Yun, TK (2001). Kenyelletso e khuts'oane ea Panax ginseng CA Meyer. Journal of Korean Medical Science, 16(Suppl), S3.


Nako ea poso: Apr-16-2024
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