Ke Eng Koro Germ Extract Spermidine?

Saense e ka Mora ho Spermidine

Spermidine ke polyamine e etsahalang ka tlhaho e bapalang karolo ea bohlokoa lits'ebetsong tsa cellular. Li-polyamine, tse kang spermidine, ke tsa bohlokoa bakeng sa khōlo, ho ikatisa le ho boloka lisele. Metsoako ena e ameha ka ho khetheha ho laola autophagy, mokhoa oo 'mele o tsosolosang le ho hloekisa lisele tse senyehileng. Mokhoa ona oa ka hare oa "ho boloka ntlo" o bohareng ba bophelo bo botle 'me hona joale o amahanngoa le ho fokotseha ho amanang le lilemo.

Liphello tse Khahlanong le Botsofali:Spermidine e 'nile ea amahanngoa le liphello tse khahlanong le botsofali, kaha e fumanoa e fokotsehile ka maemo le botsofali' me e amahanngoa le nako e khutšoanyane ea bophelo le mathata a mangata, ho kenyelletsa le ho se sebetse ha 'mele oa ho itšireletsa mafung, maemo a ho ruruha, mathata a pelo kapa tsamaiso ea methapo, le tumorigenesis.
Mosebetsi oa Immune:Spermidine e phetha karolo ea bohlokoa mosebetsing oa lisele tsa 'mele oa ho itšireletsa mafung, ho kenyelletsa le phapang le tlhokomelo ea lisele tsa T, lisele tsa B, le lisele tse bolaeang tsa tlhaho (NK). E boetse e thusa ho polarization ea macrophages ho phenotype e khahlanong le ho ruruha, kahoo e thusa ho fokotsa ho ruruha.
Tšebelisano le Gut Microbiota:Bopaki bo fana ka maikutlo a hore gut microbiota e ka kopanya spermidine ho tsoa ho li-polyamine tse ling kapa li-precursors tsa tsona. Tšebelisano ena lipakeng tsa baktheria le moamoheli e ka ama maemo a spermidine ea moamoheli le bophelo bo botle ka kakaretso.
Tšireletso ea pelo:Spermidine e bontšitse liphello tsa pelo, tse ka 'nang tsa kenya letsoho ho thibela mafu a pelo.
Neuroprotection: E boetse e bonts'itse litlamorao tsa neuroprotective, tse ka bang molemo ho loants'a mafu a neurodegenerative.
Thibelo ea Mofets'e:Ka ho susumetsa immunosurveillance ea anticancer, spermidine e ka thusa ho thibela mofetše.
Taolo ea Metabolic: Spermidine e ameha taolong ea metabolic ea polyamines, e kenyelletsang tšebelisano lipakeng tsa moamoheli le microbiota ea eona.
Liteko tsa Meriana le Tšireletseho:Kaha spermidine e teng ka tlhaho phepong ea batho, liteko tsa kliniki ho eketsa ts'ebeliso ea eona li nkuoa li ka khoneha. Ho boetse ho entsoe lipatlisiso ho lekola polokeho ea spermidine, litlamorao tsa bophelo bo botle, ho monya, metabolism, le bioprocessing.
Qetellong, spermidine ke molek'hule e nang le likarolo tse ngata tse nang le liphello tse ka 'nang tsa e-ba teng bakeng sa bophelo bo botle ba batho, ho akarelletsa le ho thibela botsofali, ho itšireletsa mafung, le ho sireletsa khahlanong le mafu a sa tšoaneng. Mekhoa ea eona ea ts'ebetso e kenyelletsa ho sebelisana le gut microbiota, lisele tsa 'mele tsa ho itšireletsa mafung le litsela tsa metabolic. Liphuputso tse ling le liteko tsa bongaka li ka 'na tsa hlahloba bokhoni ba eona e le moemeli oa phekolo.

Tlaleho ea Phepo ea Koro

Koro, e leng karolo ea ho ikatisa ea lijo-thollo tsa koro, e na le limatlafatsi tse ngata haholo. E na le vithamine E e ngata, magnesium, zinki le fiber. Leha ho le joalo, se etsang hore kokoana ea koro e be e ikhethang le ho feta ke hore e na le spermidine. Le hoja palo e nyenyane ea spermidine e le teng mehloling e sa tšoaneng ea lijo, kokoana-hloko ea koro e fana ka mokhoa o tsitsitseng, o fumanehang habonolo.

Protheine:Korong ke mohloli o motle oa protheine, e nang le li-amino acid tse robeli tsa bohlokoa, e leng se etsang hore e be mohloli o feletseng oa protheine.
Fiber:E na le fiber e qhibilihang le e sa qhibiliheng, e thusang tšilong ea lijo le ho thusa ho laola maemo a tsoekere maling.
Vithamine E:Koko ea koro ke e 'ngoe ea mehloli e ruileng ka ho fetisisa ea vithamine E, haholo-holo mofuta oa tocopherol, e leng antioxidant e matla.
Li-vithamine tsa B:Ke mohloli o ruileng oa livithamine tsa B, ho akarelletsa le thiamin (B1), riboflavin (B2), niacin (B3), pantothenic acid (B5), pyridoxine (B6), le folate (B9). Li-vithamine tsena li phetha karolo ea bohlokoa tlhahisong ea matla le ho thehoa ha lisele tse khubelu tsa mali.
Vithamine B12:Le hoja hangata e sa fumanehe lijong tsa limela, kokoana-hloko ea koro ke e 'ngoe ea mehloli e fokolang ea limela ea vithamine B12, e hlokahalang bakeng sa ts'ebetso ea methapo le tlhahiso ea DNA le RNA.
Mafura a mafura:Korong e na le tekanyo e ntle ea mafura a monounsaturated le a polyunsaturated, ho akarelletsa le omega-3 le omega-6 fatty acids, tse bohlokoa bakeng sa bophelo bo botle ba pelo.
Liminerale:Ke mohloli oa liminerale tse fapaneng tse kang magnesium, phosphorus, potasiamo, zinki, tšepe le selenium, tse bohlokoa bakeng sa mesebetsi e mengata ea 'mele.
Phytosterols:Koko ea koro e na le li-phytosterols, e leng metsoako ea limela e thusang ho theola k'holeseterole.
Li-Antioxidants:Ka ntle ho vithamine E, kokoana-hloko ea koro e boetse e na le li-antioxidants tse ling tse thusang ho sireletsa lisele ho tsoa tšenyo e bakoang ke li-radicals tsa mahala.
Lik'habohaedreite:E fana ka lik'habohaedreite tse rarahaneng, tse silehang butle-butle 'me li fana ka mohloli o tsitsitseng oa matla.
Koko ea koro e ka sebelisoa ka mekhoa e fapaneng, joalo ka tlatsetso ka li-smoothie, e fafalitsoeng holim'a lijo-thollo, kapa e le motsoako oa lintho tse besitsoeng. Ka lebaka la mafura a mangata, e ka ba rancid ha e sa bolokoe hantle, kahoo ho bohlokoa ho e boloka e le ka sehatsetsing kapa e hatselitsoeng ho boloka boleng ba eona ba phepo e nepahetseng.

 

Kamoo Koro ea Kokoana Spermidine e Sebetsang Kateng

Hang ha e jeoa, spermidine e tsoang ho motsoako oa kokoana-hloko ea koro e kenngoa 'me e qala karolo ea eona mekhoeng ea lisele. E 'ngoe ea mekhoa ea eona ea mantlha ke ho ntlafatsa ts'ebetso ea mitochondrial. Mitochondria, hangata e hlalosoang e le "matlo a matla" a sele, a ikarabella bakeng sa ho hlahisa matla. Ka ho tšehetsa mosebetsi oa mitochondrial, spermidine ha e thuse feela tlhahiso ea matla empa e boetse e thusa ho fokotsa khatello ea oxidative, e leng ntho e ka sehloohong ea botsofali. E sebetsa mona 'meleng:

Autophagy Induction:E 'ngoe ea mekhoa e ka sehloohong eo ho nahanoang hore spermidine e kenya letsoho bophelong bo botle le ho phela nako e telele ke ka ho susumetsa autophagy, mokhoa oa cellular o akarelletsang ho senyeha le ho tsosolosoa ha likarolo tsa cellular tse senyehileng. Ts'ebetso ena e amahanngoa le ho tlosoa ha li-organelle tse senyehileng le li-protein aggregates, tse ka bokellang ka lilemo le ho kenya letsoho mafu a sa tšoaneng. Ka ho khothaletsa autophagy, spermidine e ka thusa ho boloka bophelo bo botle ba lisele le ts'ebetso.

Regulation of Gene Expression:Spermidine e bontšitsoe hore e ama boemo ba acetylation ea histones le liprotheine tse ling, tse ka susumetsang liphatsa tsa lefutso. E ka thibela histone acetyltransferases (HATs), e lebisang ho deacetylation ea histones le ho ka fetola ho ngoloa ha liphatsa tsa lefutso tse amehang ho autophagy le mekhoa e meng ea lisele.

Liphello tsa Epigenetic:Spermidine e ka boela ea susumetsa epigenome ka ho fetola acetylation ea histones, e leng liprotheine tse pota-potileng DNA. Sena se ka ama tsela eo liphatsa tsa lefutso li hlahisoang ka eona, ka lebaka leo, ts'ebetso ea lisele le bophelo bo botle.

Mosebetsi oa Mitochondrial:Spermidine e hokahane le ts'ebetso e ntlafetseng ea mitochondrial, e leng bohlokoa bakeng sa tlhahiso ea matla ka har'a lisele. E ka 'na ea susumetsa tlhahiso ea mitochondria e ncha le ho ntlafatsa ho tlosoa ha tse senyehileng ka mokhoa o bitsoang mitophagy, e leng mofuta oa autophagy o tobaneng le mitochondria.

Liphello tse khahlanong le ho ruruha:Spermidine e bontšitse thepa e khahlanong le ho ruruha, e ka ba molemo ho fokotsa ho ruruha ho amanang le botsofali le mafu a sa tšoaneng a amanang le lilemo.

Tšireletso Khahlanong le Khatello ea Oxidative:Joaloka polyamine, spermidine e ka sebetsa e le antioxidant, e sireletsa lisele ho tsoa tšenyo e bakoang ke mefuta ea oksijene e sebetsang (ROS), e amehang botsofaling le maloetse a mangata a amanang le lilemo.

Kameho ho Kutloisiso ea Limatla le ho Khutla ha Lisele:Spermidine e ka boela ea phetha karolo ea litsela tsa ho lemoha limatlafatsi, tse ka susumetsang mekhoa ea lisele tse kang khōlo, ho ata le metabolism. Ho 'nile ha etsoa tlhahiso ea ho hatella senescence ea cellular, boemo ba ho tšoaroa ha lisele tse ke keng tsa fetoloa tse amanang le botsofali le mafu a amanang le lilemo.

Litekanyo tse khothalelitsoeng tsa Wheat Germ Extract Spermidine

Litsebi li khothalletsa ho kenyelletsa spermidine lijong tsa letsatsi le letsatsi ka tekanyo e nyenyane, e laoloang. Tekanyetso e khothaletsoang bakeng sa melemo e nepahetseng ea fapana, empa lithuto tse ngata li khothaletsa limiligrama tse 1 ho isa ho tse 5 ka letsatsi. Litekanyetso tse phahameng, haholo-holo ka foromo ea tlatsetso, li lokela ho sebelisoa ka hloko, 'me ho bohlokoa ho buisana le setsebi sa tlhokomelo ea bophelo pele u qala mokhoa ofe kapa ofe o mocha oa tlatsetso.

Qetello: Bokamoso bo Khanyang bo nang le Kokoana ea Koro Extract Spermidine

Ho ntšoa ha kokoana-hloko ea koro spermidine e fana ka monyetla o monate ho ba batlang ho ntlafatsa bophelo ba bona ka kakaretso le bophelo bo bolelele. Bokhoni ba eona ba ho khothaletsa nchafatso ea lisele, ho ntlafatsa ts'ebetso ea kelello, le ho ts'ehetsa ts'ebetso ea botsofali bo botle bo e beha e le tlatsetso e tšepisang. Ka lipatlisiso tse tsoelang pele, spermidine haufinyane e ka fetoha motheo oa bophelo bo botle ba thibelo.