Litaba - Na Licorice Extract Glabridin e hlile e ea sebetsa?

I. Selelekela

Indasteri ea tlhokomelo ea letlalo e thoholelitse bokhoni bo bosoeu ba "Glabridin" (e ntšitsoeng ho Glycyrrhiza glabra) kaha e feta moetapele ea soeufetseng arbutin ka makhetlo a 1164, e fumana tlotla ea "khauta e soeufatsang"! Empa na e hlile e tsoteha joalokaha e utloahala? E finyella liphello tse sa tloaelehang joang?

Ha linako tsa selemo li ntse li fetoha ’me literata li ntse li khabisoa ka “maoto a hlobotseng le matsoho a sa roala letho,” e leng taba eo batho ba chesehelang botle ba ho bua, ntle le ho itšireletsa letsatsing, e fetoha bosoeu ba letlalo.

Sebakeng sa tlhokomelo ea letlalo, ho na le metsoako e mengata ea ho soeufala, ho akarelletsa le vithamine C, niacinamide, arbutin, hydroquinone, kojic acid, tranexamic acid, glutathione, ferulic acid, phenethylresorcinol (377), le tse ling. Leha ho le joalo, motsoako oa "glabridin" o tsositse thahasello ea balateli ba bangata, e leng se etsang hore ho hlahlojoe ka botebo ho senola botumo ba eona bo ntseng bo eketseha. Ha re ke re hlahlobeng lintlha!

Ka sengoloa sena, re ikemiselitse ho sebetsana le lintlha tsa bohlokoa tse latelang:
(1) Glabridin e simolohile hokae? E amana joang le "Glycyrrhiza glabra extract"?
(2) Ke hobane’ng ha “Glabridin” e hlomphuoa e le “khauta e soeufatsang”?
(3) Melemo ea "Glabridin" ke efe?
(4) Glabridin e finyella liphello tsa eona tse tšoeu joang?
(5) Na licorice e hlile e matla joalokaha ho boletsoe?
(6) Ke lihlahisoa life tsa tlhokomelo ea letlalo tse nang leGlabridin?

No.1 Ho Tseba Tšimoloho ea "Glabridin"

Glabridin, setho sa lelapa la licorice flavonoid, e tsoa ho semela sa "Glycyrrhiza glabra". Naheng ea heso, ho na le mefuta e robeli e meholo ea licorice, e nang le mefuta e meraro e kenyellelitsoeng ho "Pharmacopoeia," e leng Ural licorice, licorice bulge, le licorice glabra. Glycyrrhizin e fumaneha feela Glycyrrhiza glabra, e sebetsa joalo ka karolo ea mantlha ea isoflavone ea semela.

Mokhoa oa sebopeho sa glycyrrhizin
E qalileng ho sibolloa ke k'hamphani ea Majapane ea MARUZEN 'me e ntšitsoe ho Glycyrrhiza glabra, glycyrrhizin e sebelisoa haholo joalo ka tlatsetso ea lihlahisoa tse soeufatsang tsa tlhokomelo ea letlalo ho pholletsa le Japane, Korea le mefuta e fapaneng ea machaba ea tlhokomelo ea letlalo. Leha ho le joalo, ho bohlokoa ho hlokomela hore motsoako o thathamisitsoeng lihlahisoa tsa skincare tseo re li sebelisang e kanna ea se be "glycyrrhizin" ka ho hlaka empa "Glycyrrhiza extract". Le hoja "Glycyrrhizin" e le ntho e le 'ngoe, "Glycyrrhiza extract" e ka kenyelletsa likaroloana tse ling tse sa kang tsa aroloa le ho hloekisoa ka ho feletseng, tse ka sebetsang e le leqheka la ho bapatsa ho hatisa litšoaneleho tsa "tlhaho" tsa sehlahisoa.

No.2 Ke hobane'ng ha licorice e bitsoa "Gold Whitener"?

Glycyrrhizin ke motsoako o sa tloaelehang le o phephetsang ho ntša. Glycyrrhiza glabra ha e fumanehe habonolo ka bongata. Ho kopantsoe le ho rarahana ha mokhoa oa ho ntša, ho ka fumanoa ligrama tse ka tlaase ho 100 ho tloha ho 1 tonne ea lithupa le makhasi a hloekileng a licorice. Khaello ena e tsamaisa boleng ba eona, e etsa hore e be e 'ngoe ea lisebelisoa tse tala tse turang ka ho fetisisa lihlahisoa tsa letlalo, tse bapisoang le khauta. Theko ea 90% ea lisebelisoa tse tala tsa motsoako ona e nyolohela ho li-yuan tse fetang 200,000/kg.
Ke ne ke hloletsoe, kahoo ke ile ka etela sebaka sa marang-rang sa Aladdin ho netefatsa lintlha. Licorice ea analytically pure (bohloeki ≥99%) e fanoa ka theko ea papatso ea 780 yuan/20mg, e lekanang le 39,000 yuan/g.
Ka motsotsoana, ke ile ka fumana tlhompho e ncha bakeng sa motsoako ona o sa ikakasang. Bosoeu ba eona bo ke keng ba lekanngoa bo entse hore e be le tlotla ea "khauta e soeufatsang" kapa "Golden Whitener".

No.3 Mosebetsi oa Glabridin ke Ofe?

Glabridin e na le mefuta e mengata ea likokoana-hloko. E sebetsa e le motsoako o sebetsang hantle, o bolokehileng, le tikoloho bakeng sa ho soeufala le ho tlosa matheba. Ho feta moo, e na le li-antibacterial, anti-inflammatory, antioxidant, anti-aging le anti-ultraviolet liphello. Bokhoni ba eona bo ikhethang ba ho soeufala, ho khanya le ho tlosa matheba bo tšehelitsoe ke data ea liteko, e senolang hore phello e soeufatsang ea Glabridin e feta ea vithamine C ka makhetlo a fetang 230, hydroquinone ka makhetlo a 16, le moemeli ea tsebahalang oa bosoeu arbutin ka 1164 e makatsang. linako.

No.4 Mokhoa o mosoeu oa glabridin ke ofe?

Ha letlalo le pepesehetse mahlaseli a ultraviolet, le etsang hore ho be le li-radicals tsa mahala, melanocyte e susumelletseha ho hlahisa tyrosinase. Tlas'a tšusumetso ea enzyme ena, tyrosine letlalong e hlahisa melanin, e lebisang letlalong le fifala ha melanin e tsamaisoa ho tloha karolong ea basal ho ea ho stratum corneum.
Molao-motheo oa mantlha oa motsoako ofe kapa ofe o soeufatsang ke ho kenella ts'ebetsong ea tlhahiso ea melanin kapa lipalangoang. Mochine o mosoeu oa Glabridin o kenyelletsa lintlha tse tharo tse latelang:
(1) Ho thibela tšebetso ea tyrosinase
Glabridin e bonts'a phello e matla ea ho thibela tšebetso ea tyrosinase, e fanang ka litholoana tse hlakileng le tse bohlokoa. Lipapiso tsa k'homphieutha li senola hore glabridin e ka tlama ka tieo setsing se sebetsang sa tyrosinase ka li-bond tsa hydrogen, e thibela ka katleho ho kena ha thepa e tala bakeng sa tlhahiso ea melanin (tyrosine), kahoo e sitisa tlhahiso ea melanin. Mokhoa ona, o tsejoang e le thibelo ea tlholisano, o tšoana le boitšisinyo bo sebete ba lerato.

(2) Ho hatella tlhahiso ea mefuta ea oksijene e sebetsang (antioxidant)
Ho pepesetsoa mahlaseli a kotsi ho etsa hore ho be le mefuta ea oksijene e sebetsang (li-radicals tsa mahala), tse ka senyang lera la phospholipid la letlalo, e leng se etsang hore ho be le erythema le pigmentation. Kahoo, mefuta ea oksijene e sebetsang e tsejoa ka ho kenya letsoho ho ntlafatseng letlalo, e leng se totobatsang bohlokoa ba ts'ireletso ea letsatsi tlhokomelong ea letlalo. Liphuputso tsa liteko li bonts'itse hore glabridin e bonts'a matla a tšoanang a mahala a scavenging ho superoxide dismutase (SOD), e sebetsa joalo ka antioxidant. Sena se thusa ho fokotsa lintlha tse tlatsetsang ho eketseha ha ts'ebetso ea tyrosinase.

(3) Ho thibela ho ruruha
Ka mor'a ho senyeha ha letlalo ho tloha mahlaseli a ultraviolet, ponahalo ea erythema le pigmentation e tsamaisana le ho ruruha, ho mpefatsa tlhahiso ea melanin le ho tsoela pele ho senya potoloho. Lintho tse khahlanong le ho ruruha tsa Glabridin li etsa hore ho be le tikoloho e ntle ea ho thibela ho thehoa ha melanin ho isa tekanyong e itseng, ha e ntse e khothalletsa ho lokisoa ha letlalo le senyehileng.

No. 5 Na Glabridin e Hlile e Matla Hakalo?

Glabridin e 'nile ea thoholetsoa e le motsoako o sebetsang hantle le oa tikoloho bakeng sa ho soeufala le ho tlosa matheba, ho ithorisa ka mokhoa o hlalositsoeng hantle oa ho soeufatsa le ho sebetsa ka mokhoa o tsotehang. Lintlha tsa liteko li bontša hore phello ea eona e tšoeu e feta ea "whitening giant" arbutin ka makhetlo a fetang sekete (joalokaha ho tlalehiloe boitsebisong ba liteko).
Bafuputsi ba ile ba etsa mohlala oa liteko tsa liphoofolo ba sebelisa zebrafish ho lekola phello ea inhibitory ea glabridin ho melanin, ho senola papiso e kholo le kojic acid le bearberry.
Ntle le liteko tsa liphoofolo, liphetho tsa kliniki li boetse li totobatsa phello e hlahelletseng ea bosoeu ea glabridin, ka liphetho tse hlokomelehang tse hlokometsoeng nakong ea libeke tsa 4-8.
Le hoja ho sebetsa ha motsoako ona oa ho soeufala ho bonahala, tšebeliso ea eona ha ea ata joaloka metsoako e meng e soeufatsang. Ka maikutlo a ka, lebaka le ka sehloohong le itšetlehile ka "boemo ba eona ba khauta" indastering-e theko e boima! Leha ho le joalo, ka mor'a tšebeliso ea lihlahisoa tse tloaelehileng tsa tlhokomelo ea letlalo, ho na le mokhoa o ntseng o eketseha oa batho ba batlang lihlahisoa tse nang le motsoako ona oa "khauta".

No.6 Ke Lihlahisoa life tsa Skincare tse Nang le Glabridin?

Boitlhotlhollo: Se latelang ke lethathamo, eseng khothaletso!
Glabridin ke motsoako o matla oa ho hlokomela letlalo o tsejoang ka thepa ea ona e khanyang letlalo. E ka fumaneha lihlahisoa tse fapaneng tsa tlhokomelo ea letlalo, ho kenyeletsoa li-serum, li-essence, lotions, le limaske. Lihlahisoa tse ling tse ka 'nang tsa e-ba le Glabridin, leha ho le joalo, ke habohlokoa ho hlokomela hore boteng ba Glabridin lihlahisoa tsa tlhokomelo ea letlalo bo ka fapana,' me ho eletsoa ho hlahloba ka hloko lethathamo la motsoako oa lihlahisoa tse itseng ho tseba hore na ke mang.
(1) Aleble Licorice Queen Body Lotion
Lethathamo la motsoako le hlahisa "Glycyrrhiza glabra" e le motsoako oa bobeli (metsi a latelang), hammoho le glycerin, sodium hyaluronate, squalane, ceramide, le likarolo tse ling tse mongobo.
(2) Bana Makeup Light Fruit Licorice Repair Essence Water
Lithako tse ka sehloohong li kenyelletsa motsoako oa Glycyrrhiza glabra, hydrolyzed algae extract, arbutin, Polygonum cuspidatum root extract, Scutellaria baicalensis root extract, le tse ling.
(3) Kokoskin Snow Clock Essence Body Serum
E na le 5% nicotinamide, 377, le glabridin e le likarolo tsa eona tsa mantlha.
(4) Licorice Facial Mask (Mefuta e fapaneng)
Sehlopha sena sa lihlahisoa sea fapana, 'me tse ling li na le chelete e fokolang 'me li rekisoa e le "glabragan" ea litlama.
(5) Letoto la Licorice la Guyu

No.7 Tlhokofatso ea Moea

(1) Na Glabridin e lihlahisoa tsa skincare e hlile e ntšitsoe ho licorice?
Potso ea hore na Glabridin ka lihlahisoa tsa skincare e hlile e ntšitsoe ho licorice ke e nepahetseng. Sebopeho sa lik'hemik'hale sa motsoako oa licorice, haholo-holo glabridin, se fapane, 'me mokhoa oa ho ntša o ka bitsa chelete e ngata. Sena se hlahisa potso ea hore na ho ka ba molemo ho feta ho nka lik'hemik'hale tsa motsoako e le mokhoa o mong oa ho fumana glabridin. Leha metsoako e meng, joalo ka artemisinin, e ka fumanoa ka ho kopanya ka botlalo, hoa khoneha ho kopanya glabridin hape. Leha ho le joalo, litšenyehelo tsa litšenyehelo tsa motsoako oa lik'hemik'hale ha li bapisoa le ho ntšoa li lokela ho nkoa. Ho feta moo, ho ka 'na ha e-ba le matšoenyeho mabapi le tšebeliso ea boomo ea "Glycyrrhiza glabra extract" lethathamong la motsoako oa lihlahisoa tsa skincare ho theha boipiletso ba tlhaho ba ho bapatsa. Ho bohlokoa ho batlisisa ka qaleho le mekhoa ea tlhahiso ea metsoako ea skincare ho netefatsa pepenene le bonnete.

(2) Na nka tlotsa licorice e hloekileng haholo sefahlehong sa ka bakeng sa 'mala o mosoeu oa lehloa?
Karabo ke che e tiileng! Le hoja phello e tšoeu ea glabridin e babatseha, thepa ea eona e fokotsa tšebeliso ea eona e tobileng. Glycyrrhizin e batla e sa qhibilihe ka metsing, 'me matla a eona a ho phunyeletsa lesela la letlalo a fokola. Ho e kenyelletsa lihlahisoa tsa skincare ho hloka ts'ebetso e matla ea tlhahiso le litokisetso. Ntle le mokhoa o nepahetseng, ho ka ba thata ho fumana phello e lakatsehang. Leha ho le joalo, lipatlisiso tsa saense li lebisitse ho nts'etsopele ea litokisetso tsa lihlooho ka mokhoa oa liposomes, ho matlafatsa ho monya le ho sebelisoa ha glabridin ka letlalo.

litšupiso:
[1] Ho hlahisa 'mala: dyschromia[M]. Thierry Passeron le Jean-Paul Ortonne, 2010.
[2] J. Chen et al. / Spectrochimica Acta Karolo ea A: Molek'hule le Biomolecular Spectroscopy 168 (2016) 111-117